Filamin A anticorps (Internal Region)

N° du produit ABIN6261749

Détail du produit anti-Filamin A anticorps

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Filamin A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Filamin A Antibody detects endogenous levels of total Filamin A.

Homologie: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Filamin A, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Filamin A

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Autre désignation: FLNA (FLNA Produits)

Synonymes: anticorps ABP-280, anticorps ABPX, anticorps CSBS, anticorps CVD1, anticorps FLN, anticorps FLN-A, anticorps FLN1, anticorps FMD, anticorps MNS, anticorps NHBP, anticorps OPD, anticorps OPD1, anticorps OPD2, anticorps XLVD, anticorps XMVD, anticorps fb98b06, anticorps wu:fb98b06, anticorps wu:fd09g03, anticorps wu:fd49a06, anticorps Dilp2, anticorps F730004A14Rik, anticorps Fln1, anticorps filamin-1, anticorps RGD1560614, anticorps MGC147094, anticorps CG3937, anticorps Cher, anticorps Dmel\\CG3937, anticorps Fil, anticorps joy, anticorps sko, anticorps filamin A, anticorps filamin A, alpha (actin binding protein 280), anticorps filamin, alpha, anticorps filamin-A, anticorps cheerio, anticorps FLNA, anticorps flna, anticorps Flna, anticorps LOC587317, anticorps cher, anticorps LOC100380643

Sujet:

Description: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

Gene: FLNA

Poids moléculaire: 280kDa

ID gène: 2316

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location