GAS8 anticorps (Internal Region)

N° du produit ABIN6261889

Détail du produit anti-GAS8 anticorps

Antigène: GAS8 (Growth Arrest-Specific 8 (GAS8))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAS8 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Specificité: GAS8 Antibody detects endogenous levels of total GAS8.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GAS8, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GAS8

Antigène: GAS8 (Growth Arrest-Specific 8 (GAS8))

Autre désignation: GAS8 (GAS8 Produits)

Synonymes: anticorps CG14271, anticorps Dmel\\CG14271, anticorps zgc:66271, anticorps wu:fb93e12, anticorps MGC114774, anticorps Gas11, anticorps GAS11, anticorps Growth arrest specific protein 8, anticorps growth arrest-specific 8, anticorps growth arrest specific 8, anticorps growth arrest specific 8 S homeolog, anticorps Gas8, anticorps gas8, anticorps GAS8, anticorps gas8.S

Sujet:

Description: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning (PubMed:26387594, PubMed:27120127, PubMed:27472056). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by faciltating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner (By similarity).

Gene: GAS8

Poids moléculaire: 56 kDa

ID gène: 2622

UniProt: O95995