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HDAC5 anticorps (C-Term)

HDAC5 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262182
  • Antigène Voir toutes HDAC5 Anticorps
    HDAC5 (Histone Deacetylase 5 (HDAC5))
    Épitope
    • 23
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 78
    • 57
    • 42
    • 33
    • 28
    • 18
    • 12
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 76
    • 2
    Lapin
    Clonalité
    • 76
    • 2
    Polyclonal
    Conjugué
    • 48
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp HDAC5 est non-conjugé
    Application
    • 69
    • 24
    • 23
    • 22
    • 21
    • 18
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    HDAC5 Antibody detects endogenous levels of total HDAC5.
    Homologie
    Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human HDAC5, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product HDAC5 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    HDAC5 (Histone Deacetylase 5 (HDAC5))
    Autre désignation
    HDAC5 (HDAC5 Produits)
    Synonymes
    anticorps HD5, anticorps NY-CO-9, anticorps AI426555, anticorps Hdac4, anticorps mHDA1, anticorps mKIAA0600, anticorps ATHDA5, anticorps HDA5, anticorps MAF19.7, anticorps MAF19_7, anticorps histone deacetylase 5, anticorps histone deacetylase 5, anticorps HDAC5, anticorps Hdac5, anticorps HDA05, anticorps hdac5
    Sujet

    Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

    Gene: HDAC5

    Poids moléculaire
    122 kDa
    ID gène
    10014
    UniProt
    Q9UQL6
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
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