HES1 anticorps (Internal Region)
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- Antigène Voir toutes HES1 Anticorps
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HES1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- HES1 Antibody detects endogenous levels of total HES1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human HES1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HES1 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
- Autre désignation
- HES1 (HES1 Produits)
- Synonymes
- anticorps HES-1, anticorps HHL, anticorps HRY, anticorps bHLHb39, anticorps Hry, anticorps HAIRY1, anticorps c-hairy1A, anticorps Xhairy1, anticorps hairy1, anticorps hes1, anticorps Xhairy-1, anticorps Xlh1, anticorps hes family bHLH transcription factor 1, anticorps hairy and enhancer of split 1 (Drosophila), anticorps hes family bHLH transcription factor 4, anticorps hes family bHLH transcription factor 1 S homeolog, anticorps hes family bHLH transcription factor 1 L homeolog, anticorps HES1, anticorps Hes1, anticorps HES4, anticorps hes1.S, anticorps hes1.L
- Sujet
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Description: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Gene: HES1
- Poids moléculaire
- 30 kDa
- ID gène
- 3280
- UniProt
- Q14469
- Pathways
- Réparation de l'ADN
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