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RBMX anticorps (N-Term)

RBMX Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262320
  • Antigène Voir toutes RBMX Anticorps
    RBMX (RNA Binding Motif Protein, X-Linked (RBMX))
    Épitope
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 22
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 22
    Lapin
    Clonalité
    • 21
    • 1
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RBMX est non-conjugé
    Application
    • 15
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    HnRNP G Antibody detects endogenous levels of total hnRNP G.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human hnRNP G, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    RBMX (RNA Binding Motif Protein, X-Linked (RBMX))
    Autre désignation
    RBMX (RBMX Produits)
    Synonymes
    anticorps hnRNP G, anticorps HNRNPG, anticorps HNRPG, anticorps RBMXP1, anticorps RBMXRT, anticorps RNMX, anticorps hnRNP-G, anticorps fc66e11, anticorps wu:fb37c07, anticorps wu:fc66e11, anticorps hnrnpg, anticorps hnrpg, anticorps rbmxp1, anticorps rbmxrt, anticorps rnmx, anticorps RBMXL1, anticorps RNA binding motif protein, X chromosome, anticorps RNA binding motif protein, X-linked, anticorps RNA binding motif protein, X-linked S homeolog, anticorps Rbmx, anticorps RBMX, anticorps rbmx, anticorps rbmx.S
    Sujet

    Description: RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter, may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion, acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single-stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation, probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the cytoplasmic TNFR1 trafficking pathways, promotes both the IL-1-beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment.

    Gene: RBMX

    Poids moléculaire
    42 kDa
    ID gène
    27316
    UniProt
    P38159
    Pathways
    Chromatin Binding, Ribonucleoprotein Complex Subunit Organization
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