ICOS anticorps (Internal Region)
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- Antigène Voir toutes ICOS Anticorps
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ICOS est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificité
- ICOS Antibody detects endogenous levels of total ICOS.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ICOS, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ICOS Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Autre désignation
- ICOS (ICOS Produits)
- Synonymes
- anticorps ICOS, anticorps AILIM, anticorps CCLP, anticorps CRP-1, anticorps H4, anticorps Ly115, anticorps CD278, anticorps CVID1, anticorps Ailim, anticorps inducible T-cell costimulator, anticorps inducible T cell co-stimulator, anticorps inducible T-cell co-stimulator, anticorps ICOS, anticorps LOC100232284, anticorps Icos
- Sujet
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Description: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
Gene: ICOS
- Poids moléculaire
- 23kDa
- ID gène
- 29851
- UniProt
- Q9Y6W8
- Pathways
- Cancer Immune Checkpoints
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