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CABLES1 anticorps (C-Term)

CABLES1 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262503
  • Antigène Voir toutes CABLES1 Anticorps
    CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
    Épitope
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 23
    • 18
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 21
    • 2
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CABLES1 est non-conjugé
    Application
    • 16
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Ik3-1 Antibody detects endogenous levels of total Ik3-1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Ik3-1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CABLES1 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
    Autre désignation
    CABLES1 (CABLES1 Produits)
    Synonymes
    anticorps CABLES1, anticorps si:dkey-2p18.3, anticorps CABL1, anticorps CABLES, anticorps HsT2563, anticorps IK3-1, anticorps Cables, anticorps ik3-1, anticorps Cdk5 and Abl enzyme substrate 1, anticorps CDK5 and Abl enzyme substrate 1, anticorps CABLES1, anticorps cables1, anticorps CpipJ_CPIJ019832, anticorps Cables1
    Sujet

    Description: Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity).

    Gene: CABLES1

    Poids moléculaire
    67 kDa
    ID gène
    91768
    UniProt
    Q8TDN4
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