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IL4 Receptor anticorps (N-Term)

IL4R Reactivité: Humain, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262528
  • Antigène Voir toutes IL4 Receptor (IL4R) Anticorps
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Épitope
    • 16
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 55
    • 42
    • 22
    Humain, Souris
    Hôte
    • 66
    • 12
    • 8
    • 2
    • 1
    Lapin
    Clonalité
    • 71
    • 17
    • 1
    Polyclonal
    Conjugué
    • 48
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp IL4 Receptor est non-conjugé
    Application
    • 75
    • 28
    • 27
    • 14
    • 14
    • 13
    • 9
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    IL4R/CD124 Antibody detects endogenous levels of total IL4R/CD124.
    Homologie
    Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human IL4R/CD124, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IL4R Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Autre désignation
    IL4R (IL4R Produits)
    Synonymes
    anticorps IL4R, anticorps il-4ra, anticorps zgc:113063, anticorps CD124, anticorps IL-4RA, anticorps IL4RA, anticorps Il4ra, anticorps IL4, anticorps Il4r, anticorps interleukin 4 receptor, anticorps interleukin 4 receptor, tandem duplicate 1, anticorps interleukin 4 receptor, alpha, anticorps IL4R, anticorps il4r.1, anticorps Il4r, anticorps Il4ra
    Sujet

    Description: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

    Gene: IL4R

    Poids moléculaire
    89 kDa
    ID gène
    3566
    UniProt
    P24394
    Pathways
    Signalistation JAK/STAT, Positive Regulation of Immune Effector Process
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