IL-6 anticorps (Internal Region)
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- Antigène Voir toutes IL-6 (IL6) Anticorps
- IL-6 (IL6) (Interleukin 6 (IL6))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-6 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- IL6 Antibody detects endogenous levels of total IL6.
- Homologie
- Bovine
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human IL6, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product IL6 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:200, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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Inflammation-mediated SOD-2 upregulation contributes to epithelial-mesenchymal transition and migration of tumor cells in aflatoxin G1-induced lung adenocarcinoma." dans: Scientific reports, Vol. 7, Issue 1, pp. 7953, (2018) (PubMed).
: "Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells." dans: Experimental cell research, Vol. 370, Issue 2, pp. 292-302, (2018) (PubMed).
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Inflammation-mediated SOD-2 upregulation contributes to epithelial-mesenchymal transition and migration of tumor cells in aflatoxin G1-induced lung adenocarcinoma." dans: Scientific reports, Vol. 7, Issue 1, pp. 7953, (2018) (PubMed).
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- Antigène
- IL-6 (IL6) (Interleukin 6 (IL6))
- Autre désignation
- IL6 (IL6 Produits)
- Synonymes
- anticorps BSF2, anticorps HGF, anticorps HSF, anticorps IFNB2, anticorps IL-6, anticorps Il-6, anticorps ILg6, anticorps Ifnb2, anticorps il6, anticorps CHIL-6, anticorps interleukin 6, anticorps interleukin-6, anticorps IL6, anticorps Il6, anticorps il-6, anticorps IL-6
- Sujet
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Description: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Gene: IL6
- Poids moléculaire
- 24kDa
- ID gène
- 3569
- UniProt
- P05231
- Pathways
- Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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