IL28RA anticorps (Internal Region)

N° du produit ABIN6262562

Détail du produit anti-IL28RA anticorps

Antigène: IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL28RA est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: IL28RA Antibody detects endogenous levels of total IL28RA.

Homologie: Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IL28RA, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur IL28RA

Antigène: IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))

Autre désignation: IFNLR1 (IL28RA Produits)

Synonymes: anticorps IFNLR1, anticorps IL28RA, anticorps crf2/12, anticorps ifnlr, anticorps il-28r1, anticorps il28ra, anticorps licr2, anticorps ifnlr1, anticorps CRF2-12, anticorps Il28ra, anticorps CRF2/12, anticorps IFNLR, anticorps IL-28R1, anticorps LICR2, anticorps RGD1562689, anticorps interferon lambda receptor 1, anticorps interferon, lambda receptor 1, anticorps interferon, lambda receptor 1 L homeolog, anticorps IFNLR1, anticorps ifnlr1, anticorps ifnlr1.L, anticorps Ifnlr1

Sujet:

Description: The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.

Gene: IFNLR1

Poids moléculaire: 58 kDa

ID gène: 163702

UniProt: Q8IU57