IRF4 anticorps (C-Term)

N° du produit ABIN6262655

Détail du produit anti-IRF4 anticorps

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: IRF4 Antibody detects endogenous levels of total IRF4.

Homologie: Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IRF4, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur IRF4

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: IRF4 (IRF4 Produits)

Synonymes: anticorps LSIRF, anticorps MUM1, anticorps NF-EM5, anticorps AI385587, anticorps IRF-4, anticorps Spip, anticorps IRF4, anticorps si:ch73-170d1.2, anticorps irf4, anticorps interferon regulatory factor 4, anticorps interferon regulatory factor 4a, anticorps Interferon regulatory factor 4, anticorps PWWP domain-containing protein MUM1, anticorps IRF4, anticorps Irf4, anticorps irf4a, anticorps irf4, anticorps LOC612320, anticorps LOC100068881

Sujet:

Description: Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).

Gene: IRF4

Poids moléculaire: 52kDa

ID gène: 3662

UniProt: Q15306

Pathways: Chromatin Binding