AIMP2 anticorps (Internal Region)

N° du produit ABIN6262712

Détail du produit anti-AIMP2 anticorps

Antigène: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: AIMP2/p38 Antibody detects endogenous levels of total AIMP2/p38.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human AIMP2/p38, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur AIMP2

Antigène: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Autre désignation: AIMP2 (AIMP2 Produits)

Synonymes: anticorps jtv1, anticorps MGC53242, anticorps pro0992, anticorps JTV1, anticorps JTV-1, anticorps P38, anticorps AA407136, anticorps AA407225, anticorps Aimp2(p38), anticorps Jtv1, anticorps aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog, anticorps aminoacyl tRNA synthetase complex-interacting multifunctional protein 2, anticorps aminoacyl tRNA synthetase complex interacting multifunctional protein 2, anticorps aimp2.L, anticorps aimp2, anticorps AIMP2, anticorps Aimp2

Sujet:

Description: Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed:19131329). Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Gene: AIMP2

Poids moléculaire: 36 kDa

ID gène: 7965

UniProt: Q13155