Kcne3 anticorps (Internal Region)

N° du produit ABIN6262743

Détail du produit anti-Kcne3 anticorps

Antigène: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kcne3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Specificité: KCNE3 Antibody detects endogenous levels of total KCNE3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human KCNE3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Kcne3

Antigène: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Autre désignation: KCNE3 (Kcne3 Produits)

Synonymes: anticorps HOKPP, anticorps HYPP, anticorps MiRP2, anticorps 2210017H05Rik, anticorps potassium voltage-gated channel subfamily E regulatory subunit 3, anticorps potassium voltage-gated channel, Isk-related subfamily, gene 3, anticorps KCNE3, anticorps Kcne3

Sujet:

Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.

Gene: KCNE3

Poids moléculaire: 12 kDa

ID gène: 10008

UniProt: Q9Y6H6