MAN1B1 anticorps (Internal Region)

N° du produit ABIN6263089

Détail du produit anti-MAN1B1 anticorps

Antigène: MAN1B1 (Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAN1B1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: MAN1B1 Antibody detects endogenous levels of total MAN1B1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MAN1B1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MAN1B1

Antigène: MAN1B1 (Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))

Autre désignation: MAN1B1 (MAN1B1 Produits)

Synonymes: anticorps erman1, anticorps mana-er, anticorps MAN1B1, anticorps ERMAN1, anticorps MANA-ER, anticorps MRT15, anticorps E430019H13Rik, anticorps ERMan1, anticorps Gm108, anticorps RGD1563595, anticorps mannosidase alpha class 1B member 1, anticorps mannosidase, alpha, class 1B, member 1 L homeolog, anticorps endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, anticorps mannosidase, alpha, class 1B, member 1, anticorps MAN1B1, anticorps man1b1.L, anticorps LOC480667, anticorps man1b1, anticorps Man1b1

Sujet:

Description: Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2.

Gene: MAN1B1

Poids moléculaire: 80kDa

ID gène: 11253

UniProt: Q9UKM7