MAP3K11 anticorps (Internal Region)

N° du produit ABIN6263276

Détail du produit anti-MAP3K11 anticorps

Antigène: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K11 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: MLK3 Antibody detects endogenous levels of total MLK3.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MLK3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MAP3K11

Antigène: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Autre désignation: MAP3K11 (MAP3K11 Produits)

Synonymes: anticorps MEKK11, anticorps MLK-3, anticorps MLK3, anticorps PTK1, anticorps SPRK, anticorps 2610017K16Rik, anticorps Mlk3, anticorps Mlk-3, anticorps RHOE, anticorps mitogen-activated protein kinase kinase kinase 11, anticorps MAP3K11, anticorps Map3k11

Sujet:

Description: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Gene: MAP3K11

Poids moléculaire: 92kDa

ID gène: 4296

UniProt: Q16584

Pathways: Signalisation MAPK, Interferon-gamma Pathway