MRC2 anticorps (N-Term)

N° du produit ABIN6263346

Détail du produit anti-MRC2 anticorps

Antigène: MRC2 (Mannose Receptor, C Type 2 (MRC2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRC2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: MRC2 Antibody detects endogenous levels of total MRC2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MRC2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MRC2

Antigène: MRC2 (Mannose Receptor, C Type 2 (MRC2))

Autre désignation: MRC2 (MRC2 Produits)

Synonymes: anticorps MRC2, anticorps cd280, anticorps uparap, anticorps clec13e, anticorps endo180, anticorps Endo180, anticorps CD280, anticorps CLEC13E, anticorps ENDO180, anticorps UPARAP, anticorps mKIAA0709, anticorps uPARAP, anticorps mannose receptor C type 2, anticorps mannose receptor, C type 2, anticorps MRC2, anticorps mrc2, anticorps Mrc2

Sujet:

Description: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Gene: MRC2

Poids moléculaire: 167kDa

ID gène: 9902

UniProt: Q9UBG0