NFATC1 anticorps (Internal Region)

N° du produit ABIN6263626

Détail du produit anti-NFATC1 anticorps

Antigène: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFATC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: NFAT2 Antibody detects endogenous levels of total NFAT2.

Homologie: Pig,Bovine,Horse,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NFAT2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NFATC1

Antigène: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Autre désignation: NFATC1 (NFATC1 Produits)

Synonymes: anticorps nf-atc, anticorps nfat2, anticorps nfatc, anticorps si:ch211-198c22.2, anticorps NFATC1, anticorps 2210017P03Rik, anticorps AI449492, anticorps AV076380, anticorps NF-ATc, anticorps NFAT2, anticorps NFATc, anticorps Nfatcb, anticorps NF-ATC, anticorps NF-ATc1, anticorps NFAT, anticorps NFATmac, anticorps nuclear factor of activated T-cells 1, anticorps nuclear factor of activated T-cells 1 L homeolog, anticorps nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, anticorps NFATC1, anticorps nfatc1.L, anticorps nfatc1, anticorps Nfatc1

Sujet:

Description: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).

Gene: NFATC1

Poids moléculaire: 78kDa,101kDa

ID gène: 4772

UniProt: O95644

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway