ZC3HC1 anticorps (C-Term)

N° du produit ABIN6263640

Détail du produit anti-ZC3HC1 anticorps

Antigène: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZC3HC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: NIPA Antibody detects endogenous levels of total NIPA.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NIPA, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ZC3HC1

Antigène: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Autre désignation: ZC3HC1 (ZC3HC1 Produits)

Synonymes: anticorps 1110054L24Rik, anticorps AU018540, anticorps AU019789, anticorps HSPC216, anticorps Nipa, anticorps NIPA, anticorps RGD1561099, anticorps zinc finger, C3HC type 1, anticorps zinc finger C3HC-type containing 1, anticorps zinc finger, C3HC-type containing 1, anticorps Zc3hc1, anticorps ZC3HC1

Sujet:

Description: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

Gene: ZC3HC1

Poids moléculaire: 55kDa

ID gène: 51530

UniProt: Q86WB0