Neuroligin 2 anticorps

N° du produit ABIN6263654

Détail du produit anti-Neuroligin 2 anticorps

Antigène: Neuroligin 2 (NLGN2)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuroligin 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: NLGN2 Antibody detects endogenous levels of total NLGN2

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NLGN2

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur Neuroligin 2

Antigène: Neuroligin 2 (NLGN2)

Autre désignation: NLGN2 (NLGN2 Produits)

Synonymes: anticorps Nlgn2, anticorps GB10066, anticorps NLGN2, anticorps CCE-L2, anticorps NV50031, anticorps Nv123771, anticorps NL2, anticorps RP23-422L16.24, anticorps neuroligin 2, anticorps LOC410779, anticorps NLGN2, anticorps LOC663865, anticorps LOC100123771, anticorps Nlgn2

Sujet:

Description: Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing. Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion (By similarity).

Gene: NLGN2

Poids moléculaire: 91 kDa

ID gène: 57555

UniProt: Q8NFZ4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane