NR2C1 anticorps (N-Term)
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- Antigène Voir toutes NR2C1 Anticorps
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR2C1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- NR2C1 Antibody detects endogenous levels of total NR2C1.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human NR2C1, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NR2C1 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
- Autre désignation
- NR2C1 (NR2C1 Produits)
- Synonymes
- anticorps TR2, anticorps NR2C1, anticorps dor2, anticorps tr2-11, anticorps xDOR2, anticorps DKFZp468M0512, anticorps si:dkey-183c16.2, anticorps zgc:110672, anticorps 4831444H07Rik, anticorps 80.3, anticorps Eenr, anticorps Tr2-11, anticorps Tr2, anticorps Psg4, anticorps TR2-11, anticorps PSG9, anticorps nr2c1, anticorps nuclear receptor subfamily 2 group C member 1, anticorps nuclear receptor subfamily 2 group C member 1 S homeolog, anticorps nuclear receptor subfamily 2, group C, member 1, anticorps pregnancy specific beta-1-glycoprotein 4, anticorps nuclear receptor subfamily 2 group C member 1 L homeolog, anticorps NR2C1, anticorps nr2c1.S, anticorps nr2c1, anticorps Nr2c1, anticorps PSG4, anticorps nr2c1.L
- Sujet
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Description: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Gene: NR2C1
- Poids moléculaire
- 67 kDa
- ID gène
- 7181
- UniProt
- P13056
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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