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NR2C1 anticorps (N-Term)

NR2C1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6263718
  • Antigène Voir toutes NR2C1 Anticorps
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    Épitope
    • 13
    • 12
    • 9
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 65
    • 16
    • 11
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 58
    • 8
    Lapin
    Clonalité
    • 62
    • 4
    Polyclonal
    Conjugué
    • 39
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NR2C1 est non-conjugé
    Application
    • 57
    • 29
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    NR2C1 Antibody detects endogenous levels of total NR2C1.
    Homologie
    Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human NR2C1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product NR2C1 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    Autre désignation
    NR2C1 (NR2C1 Produits)
    Synonymes
    anticorps TR2, anticorps NR2C1, anticorps dor2, anticorps tr2-11, anticorps xDOR2, anticorps DKFZp468M0512, anticorps si:dkey-183c16.2, anticorps zgc:110672, anticorps 4831444H07Rik, anticorps 80.3, anticorps Eenr, anticorps Tr2-11, anticorps Tr2, anticorps Psg4, anticorps TR2-11, anticorps PSG9, anticorps nr2c1, anticorps nuclear receptor subfamily 2 group C member 1, anticorps nuclear receptor subfamily 2 group C member 1 S homeolog, anticorps nuclear receptor subfamily 2, group C, member 1, anticorps pregnancy specific beta-1-glycoprotein 4, anticorps nuclear receptor subfamily 2 group C member 1 L homeolog, anticorps NR2C1, anticorps nr2c1.S, anticorps nr2c1, anticorps Nr2c1, anticorps PSG4, anticorps nr2c1.L
    Sujet

    Description: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

    Gene: NR2C1

    Poids moléculaire
    67 kDa
    ID gène
    7181
    UniProt
    P13056
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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