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NRF2 anticorps (N-Term)

NFE2L2 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6263730
  • Antigène Voir toutes NRF2 (NFE2L2) Anticorps
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    Épitope
    • 23
    • 15
    • 8
    • 8
    • 8
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 121
    • 56
    • 54
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 114
    • 9
    • 1
    Lapin
    Clonalité
    • 104
    • 20
    Polyclonal
    Conjugué
    • 59
    • 10
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NRF2 est non-conjugé
    Application
    • 97
    • 51
    • 31
    • 29
    • 20
    • 18
    • 15
    • 15
    • 14
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Nrf2 Antibody detects endogenous levels of total Nrf2.
    Homologie
    Pig,Bovine,Horse,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Nrf2, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product NFE2L2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Zheng, Feng, Jiang, Wu, Tang, Kuang, Zeng, Zhou, Liu: "Selenium deficiency impaired immune function of the immune organs in young grass carp (Ctenopharyngodon idella)." dans: Fish & shellfish immunology, Vol. 77, pp. 53-70, (2018) (PubMed).

  • Antigène
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    Autre désignation
    NFE2L2 (NFE2L2 Produits)
    Synonymes
    anticorps Nrf2, anticorps nfe2l2, anticorps wu:fc15g09, anticorps wu:fj67e03, anticorps NF-E2R2, anticorps NRF2, anticorps AI194320, anticorps nuclear factor, erythroid 2-like 2a, anticorps nuclear factor, erythroid 2 like 2 S homeolog, anticorps nuclear factor, erythroid 2 like 2, anticorps nuclear factor, erythroid derived 2, like 2, anticorps nuclear factor, erythroid 2-like 2, anticorps nfe2l2a, anticorps nfe2l2.S, anticorps NFE2L2, anticorps Nfe2l2
    Sujet

    Description: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

    Gene: NFE2L2

    Poids moléculaire
    100kDa
    ID gène
    4780
    UniProt
    Q16236
    Pathways
    ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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