OMA1 anticorps (Internal Region)

N° du produit ABIN6263821

Détail du produit anti-OMA1 anticorps

Antigène: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OMA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: OMA1 Antibody detects endogenous levels of total OMA1.

Homologie: Zebrafish,Bovine,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human OMA1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur OMA1

Antigène: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Autre désignation: OMA1 (OMA1 Produits)

Synonymes: anticorps 2010001O09Rik, anticorps DAB1, anticorps MPRP-1, anticorps YKR087C, anticorps ZMPOMA1, anticorps peptidase, anticorps RGD1304821, anticorps oma1, anticorps OMA1 zinc metallopeptidase, anticorps si:ch73-215a11.1, anticorps olfactory receptor 4K2, anticorps OMA1, anticorps Oma1, anticorps si:ch73-215a11.1, anticorps LOC531304

Sujet:

Description: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

Gene: OMA1

Poids moléculaire: 60 kDa

ID gène: 115209

UniProt: Q96E52