ABCB1 anticorps (Internal Region)

N° du produit ABIN6263928

Détail du produit anti-ABCB1 anticorps

Antigène: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: P Glycoprotein 1(MDR1) Antibody detects endogenous levels of total P Glycoprotein 1(MDR1).

Homologie: Pig,Horse,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human P Glycoprotein 1(MDR1), corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-ABCB1 (ABIN6263928)

Shao, Zhang, Ma, Lu, Meng, Li, Wang, Chen, Zhang, Han, Liu, Ma: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." dans: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).

Liu, Tang, Liu, Zhang, He, Li, Gao, Tang, Jin, Kong: "Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance." dans: Cell death & disease, Vol. 9, Issue 4, pp. 419, (2018) (PubMed).

Xiang, Ye, Huang, Yu, Chen, Deng, Zhang, Lou, Zhang, Shi, Chen, Zhou: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).

Zhou, Lin, Zhang, Zhang, Zhang, Zhang, Xie, Ren: "miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression." dans: Cell proliferation, Vol. 50, Issue 3, (2017) (PubMed).

Détails sur ABCB1

Antigène: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Autre désignation: ABCB1 (ABCB1 Produits)

Synonymes: anticorps ABC20, anticorps CD243, anticorps CLCS, anticorps GP170, anticorps MDR1, anticorps P-GP, anticorps PGY1, anticorps Abcb1, anticorps Mdr1a, anticorps p-gp, anticorps xemdr, anticorps Mdr1, anticorps Mdr1b, anticorps Pgy-1, anticorps Pgy1, anticorps mdr, anticorps ABCB1, anticorps PGP1, anticorps ATP binding cassette subfamily B member 1, anticorps ATP binding cassette subfamily B member 1A, anticorps ATP binding cassette subfamily B member 1 L homeolog, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 1B, anticorps ABCB1, anticorps Abcb1a, anticorps abcb1.L, anticorps Abcb1b, anticorps Abcb1

Sujet:

Description: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

Gene: ABCB1

Poids moléculaire: 141 kDa

ID gène: 5243

UniProt: P08183