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PDZK1 anticorps (C-Term)

PDZK1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6264124
  • Antigène Voir toutes PDZK1 Anticorps
    PDZK1 (PDZ Domain Containing 1 (PDZK1))
    Épitope
    • 12
    • 8
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 50
    • 23
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 44
    • 7
    • 1
    • 1
    Lapin
    Clonalité
    • 46
    • 7
    Polyclonal
    Conjugué
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PDZK1 est non-conjugé
    Application
    • 49
    • 24
    • 17
    • 13
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    PDZK1 Antibody detects endogenous levels of total PDZK1.
    Homologie
    Bovine,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human PDZK1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PDZK1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    PDZK1 (PDZ Domain Containing 1 (PDZK1))
    Autre désignation
    PDZK1 (PDZK1 Produits)
    Synonymes
    anticorps xpdzk1, anticorps PDZK1, anticorps CAP70, anticorps CLAMP, anticorps NHERF-3, anticorps NHERF3, anticorps PDZD1, anticorps 1700023D20Rik, anticorps 2610507N21Rik, anticorps 4921513F16Rik, anticorps AI267131, anticorps AI314638, anticorps AL022680, anticorps D3Ertd537e, anticorps Pdzd1, anticorps mPDZK1, anticorps Clamp, anticorps PDZ domain containing 1, anticorps PDZ domain containing 1 L homeolog, anticorps PDZK1, anticorps pdzk1.L, anticorps pdzk1, anticorps Pdzk1
    Sujet

    Description: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).

    Gene: PDZK1

    Poids moléculaire
    57kDa
    ID gène
    5174
    UniProt
    Q5T2W1
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