PPP1CB anticorps

N° du produit ABIN6264381

Détail du produit anti-PPP1CB anticorps

Antigène: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1CB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: PPP1CB Antibody detects endogenous levels of total PPP1CB

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PPP1CB

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur PPP1CB

Antigène: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Autre désignation: PPP1CB (PPP1CB Produits)

Synonymes: anticorps PP-1B, anticorps PP1B, anticorps PP1beta, anticorps PPP1CD, anticorps 1200010B19, anticorps ik:tdsubc_2f2, anticorps si:zc214p16.4, anticorps wu:fa09h01, anticorps wu:fa11e06, anticorps xx:tdsubc_2f2, anticorps PP2CB, anticorps Ppp1cb, anticorps protein phosphatase 1 catalytic subunit beta, anticorps protein phosphatase 1, catalytic subunit, beta isoform, anticorps protein phosphatase 1, catalytic subunit, beta isozyme L homeolog, anticorps protein phosphatase 1, catalytic subunit, beta isozyme, anticorps serine/threonine-protein phosphatase PP1-beta catalytic subunit, anticorps protein phosphatase 1B, magnesium dependent, beta isoform, anticorps PPP1CB, anticorps Ppp1cb, anticorps ppp1cb.L, anticorps ppp1cb, anticorps LOC100224238, anticorps Ppm1b

Sujet:

Description: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).

Gene: PPP1CB

Poids moléculaire: 37kDa

ID gène: 5500

UniProt: P62140

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism