PSMC4 anticorps (C-Term)

N° du produit ABIN6264481

Détail du produit anti-PSMC4 anticorps

Antigène: PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: PSMC4 Antibody detects endogenous levels of total PSMC4.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PSMC4, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PSMC4

Antigène: PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))

Autre désignation: PSMC4 (PSMC4 Produits)

Synonymes: anticorps NCU02260.1, anticorps AO090003000692, anticorps DDBDRAFT_0188209, anticorps DDBDRAFT_0191435, anticorps DDB_0188209, anticorps DDB_0191435, anticorps MIP224, anticorps RPT3, anticorps S6, anticorps TBP-7, anticorps TBP7, anticorps CIP21, anticorps Tbp7, anticorps 26S protease regulatory subunit 6B, anticorps regulatory particle, ATPase-like-3, anticorps 26S proteasome regulatory subunit 6B, anticorps proteasome 26S subunit, ATPase 4, anticorps proteasome (prosome, macropain) 26S subunit, ATPase, 4, anticorps LOC732870, anticorps rpt-3, anticorps ATEG_04674, anticorps LELG_01296, anticorps HCAG_00039, anticorps LOC5568998, anticorps GL50803_7950, anticorps EDI_044950, anticorps AOR_1_1218154, anticorps PTRG_03339, anticorps psmC4, anticorps prs6b, anticorps LOC100381342, anticorps psmc4, anticorps PSMC4, anticorps Psmc4

Sujet:

Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Gene: PSMC4

Poids moléculaire: 47kDa

ID gène: 5704

UniProt: P43686

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway