PTGES3 anticorps (C-Term)

N° du produit ABIN6264507

Détail du produit anti-PTGES3 anticorps

Antigène: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGES3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: P23 Antibody detects endogenous levels of total p23.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human p23, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PTGES3

Antigène: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Autre désignation: PTGES3 (PTGES3 Produits)

Synonymes: anticorps P23, anticorps TEBP, anticorps cPGES, anticorps PTGES3, anticorps 5730442A20Rik, anticorps Ptges, anticorps Tebp, anticorps p23, anticorps sid3177, anticorps RGD1561913, anticorps CPGES, anticorps cPGES-1, anticorps ptges3, anticorps wu:fb98d06, anticorps zgc:65804, anticorps zgc:77131, anticorps tebp, anticorps wu:fb50a04, anticorps zgc:86751, anticorps prostaglandin E synthase 3, anticorps prostaglandin E synthase 3 (cytosolic) pseudogene, anticorps prostaglandin E synthase 3a (cytosolic), anticorps prostaglandin E synthase 3 L homeolog, anticorps prostaglandin E synthase 3b (cytosolic), anticorps PTGES3, anticorps LOC743066, anticorps Ptges3, anticorps ptges3a, anticorps ptges3.L, anticorps ptges3b

Sujet:

Description: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).

Gene: PTGES3

Poids moléculaire: 19kDa

ID gène: 10728

UniProt: Q15185

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cellular Glucan Metabolic Process