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RANBP1 anticorps (N-Term)

RANBP1 Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6264631
  • Antigène Voir toutes RANBP1 Anticorps
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    Épitope
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 40
    • 20
    • 18
    • 3
    • 1
    • 1
    Humain, Souris
    Hôte
    • 39
    • 1
    Lapin
    Clonalité
    • 40
    Polyclonal
    Conjugué
    • 19
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RANBP1 est non-conjugé
    Application
    • 30
    • 14
    • 8
    • 6
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    RanBP1 Antibody detects endogenous levels of total RanBP1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human RanBP1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RANBP1 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    Autre désignation
    RANBP1 (RANBP1 Produits)
    Synonymes
    anticorps MGC64314, anticorps zeh1094, anticorps zgc:85649, anticorps hm:zeh1094, anticorps wu:fa96a09, anticorps wu:fj39g07, anticorps HTF9A, anticorps Htf9a, anticorps RAN binding protein 1 S homeolog, anticorps RAN binding protein 1 L homeolog, anticorps ran binding protein 1, anticorps RAN binding protein 1, anticorps ran-specific GTPase-activating protein pseudogene, anticorps ranbp1.S, anticorps ranbp1.L, anticorps PVX_090070, anticorps GL50803_16969, anticorps LOC100343953, anticorps ranbp1, anticorps RANBP1, anticorps Ranbp1
    Sujet

    Description: Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed:20485264). Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN (PubMed:17671426). Does not increase the RAN GTPase activity by itself, but increases GTP hydrolysis mediated by RANGAP1 (PubMed:7882974). Inhibits RCC1-dependent exchange of RAN-bound GDP by GTP (PubMed:7882974, PubMed:7616957).

    Gene: RANBP1

    Poids moléculaire
    23 kDa
    ID gène
    5902
    UniProt
    P43487
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