Retinoic Acid Receptor gamma anticorps

N° du produit ABIN6264704

Détail du produit anti-Retinoic Acid Receptor gamma anticorps

Antigène: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoic Acid Receptor gamma est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Retinoic Acid Receptor / Antibody detects endogenous levels of Retinoic Acid Receptor /

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Retinoic Acid Receptor /

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur Retinoic Acid Receptor gamma

Antigène: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Autre désignation: Retinoic Acid Receptor (RARG Produits)

Synonymes: anticorps NR1B3, anticorps RARC, anticorps AI385767, anticorps Nr1b3, anticorps RARD, anticorps RARgamma2, anticorps RARG, anticorps etID309710.23, anticorps etID33387.23, anticorps rarg, anticorps rarg2, anticorps wu:fb01e02, anticorps wu:fb01f03, anticorps wu:fc35a09, anticorps nr1b3, anticorps RARgamma-B, anticorps retinoic acid receptor gamma, anticorps retinoic acid receptor, gamma, anticorps retinoic acid receptor gamma a, anticorps retinoic acid receptor gamma S homeolog, anticorps retinoic acid receptor, gamma b, anticorps RARG, anticorps Rarg, anticorps rarga, anticorps rarg.S, anticorps rargb

Sujet:

Description: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).

Gene: RARA

Poids moléculaire: 50kDa

ID gène: 5914

UniProt: P10276, P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size