RGS17 anticorps (N-Term)

N° du produit ABIN6264721

Détail du produit anti-RGS17 anticorps

Antigène: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: RGS17 Antibody detects endogenous levels of total RGS17.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RGS17, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RGS17

Antigène: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Autre désignation: RGS17 (RGS17 Produits)

Synonymes: anticorps RGS17, anticorps zgc:92802, anticorps MGC179306, anticorps RGS-17, anticorps RGSZ2, anticorps hRGS17, anticorps 6430507P11Rik, anticorps Rgsz2, anticorps regulator of G protein signaling 17, anticorps regulator of G-protein signaling 17, anticorps RGS17, anticorps Rgs17, anticorps rgs17

Sujet:

Description: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).

Gene: RGS17

Poids moléculaire: 24 kDa

ID gène: 26575

UniProt: Q9UGC6

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling