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ROS1 anticorps (C-Term)

ROS1 Reactivité: Humain, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6264807
  • Antigène Voir toutes ROS1 Anticorps
    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
    Épitope
    • 16
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 43
    • 27
    • 25
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 49
    • 5
    • 1
    Lapin
    Clonalité
    • 49
    • 6
    Polyclonal
    Conjugué
    • 23
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ROS1 est non-conjugé
    Application
    • 33
    • 19
    • 14
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    ROS Antibody detects endogenous levels of total ROS.
    Homologie
    Pig,Horse,Sheep
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human ROS, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ROS1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
    Autre désignation
    ROS1 (ROS1 Produits)
    Synonymes
    anticorps MCF3, anticorps ROS, anticorps c-ros-1, anticorps ROS1C, anticorps Ros-1, anticorps c-ros, anticorps ROS proto-oncogene 1, receptor tyrosine kinase, anticorps ROS proto-oncogene 1 , receptor tyrosine kinase, anticorps Ros1 proto-oncogene, anticorps ROS1, anticorps Ros1
    Sujet

    Description: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

    Gene: ROS1

    Poids moléculaire
    263kDa
    ID gène
    6098
    UniProt
    P08922
    Pathways
    Signalisation RTK
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