POLR3K anticorps (Internal Region)
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- Antigène Voir toutes POLR3K Anticorps
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp POLR3K est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- RPC10 Antibody detects endogenous levels of total RPC10.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human RPC10, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product POLR3K Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
- Autre désignation
- POLR3K (POLR3K Produits)
- Synonymes
- anticorps MGC108467, anticorps POLR3K, anticorps 12.3kDa, anticorps 1500004O14Rik, anticorps AI196849, anticorps AU014893, anticorps C11, anticorps RPC10, anticorps RPC11, anticorps C11-RNP3, anticorps RPC12.5, anticorps hRPC11, anticorps RNA polymerase III subunit K, anticorps polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog, anticorps polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa, anticorps polymerase (RNA) III (DNA directed) polypeptide K, anticorps Polr3k, anticorps polr3k.S, anticorps polr3k, anticorps POLR3K
- Sujet
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Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Gene: POLR3K
- Poids moléculaire
- 12 kDa
- ID gène
- 51728
- UniProt
- Q9Y2Y1
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