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RYR2 anticorps (Internal Region)

RYR2 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6264892
  • Antigène Voir toutes RYR2 Anticorps
    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
    Épitope
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 27
    • 18
    • 18
    • 3
    Humain, Souris, Rat
    Hôte
    • 26
    • 1
    Lapin
    Clonalité
    • 26
    • 1
    Polyclonal
    Conjugué
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RYR2 est non-conjugé
    Application
    • 12
    • 10
    • 10
    • 9
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    RYR2 Antibody detects endogenous levels of total RYR2.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human RYR2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RYR2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol. .
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
    Autre désignation
    RYR2 (RYR2 Produits)
    Synonymes
    anticorps RYR2, anticorps ARVC2, anticorps ARVD2, anticorps RYR-2, anticorps RyR, anticorps VTSIP, anticorps 9330127I20Rik, anticorps ryanodine receptor 2, anticorps ryanodine receptor 2, cardiac, anticorps RYR2, anticorps Ryr2
    Sujet

    Description: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

    Gene: RYR2

    Poids moléculaire
    564 kDa
    ID gène
    6262
    UniProt
    Q92736
    Pathways
    Myometrial Relaxation and Contraction
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