SENP3 anticorps (Internal Region)

N° du produit ABIN6264985

Détail du produit anti-SENP3 anticorps

Antigène: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SENP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: SENP3 Antibody detects endogenous levels of total SENP3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SENP3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SENP3

Antigène: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Autre désignation: SENP3 (SENP3 Produits)

Synonymes: anticorps SMT3IP1, anticorps SSP3, anticorps Ulp1, anticorps AA408656, anticorps Smt3ip, anticorps Smt3ip1, anticorps ssp3, anticorps smt3ip1, anticorps fa03d07, anticorps wu:fa03d07, anticorps senp3, anticorps SUMO1/sentrin/SMT3 specific peptidase 3, anticorps SUMO/sentrin specific peptidase 3, anticorps Sumo1/sentrin/SMT3 specific peptidase 3, anticorps SUMO1/sentrin/SMT3 specific peptidase 3b, anticorps SUMO1/sentrin/SMT3 specific peptidase 3 L homeolog, anticorps SENP3, anticorps Senp3, anticorps senp3, anticorps senp3b, anticorps senp3.L

Sujet:

Description: Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Gene: SENP3

Poids moléculaire: 65 kDa

ID gène: 26168

UniProt: Q9H4L4