SIN3B anticorps (Internal Region)

N° du produit ABIN6265088

Détail du produit anti-SIN3B anticorps

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIN3B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificité: Sin3B Antibody detects endogenous levels of total Sin3B.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Sin3B, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SIN3B

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Autre désignation: SIN3B (SIN3B Produits)

Synonymes: anticorps fj63d08, anticorps si:dkey-6n6.6, anticorps wu:fj63d08, anticorps 2810430C10Rik, anticorps SIN3 transcription regulator family member B, anticorps SIN3 transcription regulator family member B S homeolog, anticorps transcriptional regulator, SIN3B (yeast), anticorps sin3b, anticorps SIN3B, anticorps sin3b.S, anticorps Sin3b

Sujet:

Description: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.

Gene: SIN3B

Poids moléculaire: 130kDa

ID gène: 23309

UniProt: O75182