SLC8A1 anticorps (Internal Region)

N° du produit ABIN6265150

Détail du produit anti-SLC8A1 anticorps

Antigène: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC8A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: SLC8A1 Antibody detects endogenous levels of total SLC8A1.

Homologie: Pig,Bovine,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SLC8A1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SLC8A1

Antigène: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Autre désignation: SLC8A1 (SLC8A1 Produits)

Synonymes: anticorps NCX1, anticorps AI852629, anticorps AV344025, anticorps D930008O12Rik, anticorps Ncx1, anticorps Ncx, anticorps SLC8A1, anticorps ncx1n, anticorps solute carrier family 8 member A1, anticorps solute carrier family 8 (sodium/calcium exchanger), member 1, anticorps solute carrier family 8 (sodium/calcium exchanger), member 1b, anticorps sodium/calcium exchanger 1, anticorps SLC8A1, anticorps Slc8a1, anticorps slc8a1b, anticorps Tsp_07038

Sujet:

Description: Mediates the exchange of one Ca2+ ion against three to four Na+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca2+ levels and Ca2+-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165). Contributes to Ca2+ transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca2+ levels due to release of Ca2+ stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca2+ from the cell during the next phase, so that cytoplasmic Ca2+ levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions.

Gene: SLC8A1

Poids moléculaire: 109kDa

ID gène: 6546

UniProt: P32418

Pathways: Myometrial Relaxation and Contraction