SMAD6 anticorps (Internal Region)
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- Antigène Voir toutes SMAD6 Anticorps
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SMAD6 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- SMAD6 Antibody detects endogenous levels of total SMAD6.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human SMAD6, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SMAD6 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Autre désignation
- SMAD6 (SMAD6 Produits)
- Synonymes
- anticorps madh6, anticorps madh7, anticorps Xsmad6, anticorps hst17432, anticorps AOVD2, anticorps HsT17432, anticorps MADH6, anticorps MADH7, anticorps Madh6, anticorps b2b390Clo, anticorps Smad6-like, anticorps smad6, anticorps wu:fb22g05, anticorps SMAD family member 6, anticorps SMAD family member 6a, anticorps smad6, anticorps SMAD6, anticorps Smad6, anticorps smad6a
- Sujet
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Description: Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.
Gene: SMAD6
- Poids moléculaire
- 53 kDa
- ID gène
- 4091
- UniProt
- O43541
- Pathways
- Chromatin Binding
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