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SREBF2 anticorps (Internal Region)

SREBF2 Reactivité: Humain, Rat, Souris WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265283
  • Antigène Voir toutes SREBF2 Anticorps
    SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
    Épitope
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 66
    • 31
    • 30
    • 15
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 58
    • 8
    • 1
    Lapin
    Clonalité
    • 60
    • 7
    Polyclonal
    Conjugué
    • 32
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SREBF2 est non-conjugé
    Application
    • 52
    • 28
    • 21
    • 18
    • 11
    • 9
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    SREBP2 Antibody detects endogenous levels of total SREBP2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human SREBP2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SREBF2 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
    Autre désignation
    SREBF2 (SREBF2 Produits)
    Synonymes
    anticorps SREBF2, anticorps srebp2, anticorps SREBP2, anticorps zgc:158371, anticorps AI608257, anticorps SREBP-2, anticorps SREBP2gc, anticorps bHLHd2, anticorps lop13, anticorps nuc, anticorps Srebf2_retired, anticorps sterol regulatory element binding transcription factor 2, anticorps sterol regulatory element binding factor 2, anticorps sterol regulatory element binding transcription factor 2 L homeolog, anticorps SREBF2, anticorps srebf2, anticorps Srebf2, anticorps srebf2.L
    Sujet

    Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.

    Gene: SREBF2

    Poids moléculaire
    124kDa
    ID gène
    6721
    UniProt
    Q12772
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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