STAM2 anticorps

N° du produit ABIN6265306

Détail du produit anti-STAM2 anticorps

Antigène: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: STAM2 Antibody detects endogenous levels of total STAM2

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human STAM2

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur STAM2

Antigène: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Autre désignation: STAM2 (STAM2 Produits)

Synonymes: anticorps Hbp, anticorps STAM2A, anticorps STAM2B, anticorps 1200004O12Rik, anticorps 5730456G07Rik, anticorps BB145015, anticorps stam2, anticorps MGC52950, anticorps zgc:103628, anticorps signal transducing adaptor molecule 2, anticorps signal transducing adaptor molecule (SH3 domain and ITAM motif) 2, anticorps signal transducing adaptor molecule 2 S homeolog, anticorps STAM2, anticorps Stam2, anticorps stam2.S, anticorps stam2

Sujet:

Description: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).

Gene: STAM2

Poids moléculaire: 58kDa

ID gène: 10254

UniProt: O75886

Pathways: EGFR Signaling Pathway, EGFR Downregulation