TLE1 anticorps (Internal Region)

N° du produit ABIN6265592

Détail du produit anti-TLE1 anticorps

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: TLE1 Antibody detects endogenous levels of total TLE1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TLE1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TLE1

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Autre désignation: TLE1 (TLE1 Produits)

Synonymes: anticorps ESG, anticorps ESG1, anticorps GRG1, anticorps C230057C06Rik, anticorps Estm14, anticorps Grg1, anticorps Tle4l, anticorps TLE1, anticorps transducin like enhancer of split 1, anticorps transducin-like enhancer protein 1, anticorps transducin-like enhancer of split 1, anticorps transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila), anticorps TLE1, anticorps Smp_150080, anticorps Tle1, anticorps LOC100354911, anticorps LOC100524475, anticorps LOC100061341

Sujet:

Description: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Gene: TLE1

Poids moléculaire: 83kDa

ID gène: 7088

UniProt: Q04724

Pathways: Signalisation WNT, SARS-CoV-2 Protein Interactome