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TLR3 anticorps (C-Term)

TLR3 Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265599
  • Antigène Voir toutes TLR3 Anticorps
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Épitope
    • 16
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 98
    • 68
    • 30
    • 6
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 86
    • 31
    • 5
    • 2
    Lapin
    Clonalité
    • 89
    • 35
    Polyclonal
    Conjugué
    • 53
    • 18
    • 16
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TLR3 est non-conjugé
    Application
    • 84
    • 45
    • 38
    • 35
    • 24
    • 18
    • 16
    • 15
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificité
    TLR3 Antibody detects endogenous levels of total TLR3.
    Homologie
    Bovine,Horse,Sheep,Rabbit
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human TLR3, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product TLR3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Autre désignation
    TLR3 (TLR3 Produits)
    Synonymes
    anticorps CD283, anticorps IIAE2, anticorps AI957183, anticorps zgc:123006, anticorps toll like receptor 3, anticorps toll-like receptor 3, anticorps TLR3, anticorps Tlr3, anticorps tlr3
    Sujet

    Description: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.

    Gene: TLR3

    Poids moléculaire
    99kDa
    ID gène
    7098
    UniProt
    O15455
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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