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TRIM24 anticorps (C-Term)

TRIM24 Reactivité: Humain, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265731
  • Antigène Voir toutes TRIM24 Anticorps
    TRIM24 (Tripartite Motif Containing 24 (TRIM24))
    Épitope
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 61
    • 23
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain, Souris
    Hôte
    • 57
    • 5
    • 1
    Lapin
    Clonalité
    • 56
    • 7
    Polyclonal
    Conjugué
    • 37
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TRIM24 est non-conjugé
    Application
    • 43
    • 25
    • 12
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    TRIM24 Antibody detects endogenous levels of total TRIM24.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human TRIM24, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    TRIM24 (Tripartite Motif Containing 24 (TRIM24))
    Autre désignation
    TRIM24 (TRIM24 Produits)
    Synonymes
    anticorps TRIM24, anticorps PTC6, anticorps RNF82, anticorps TF1A, anticorps TIF1, anticorps TIF1A, anticorps TIF1ALPHA, anticorps hTIF1, anticorps ptc6, anticorps rnf82, anticorps tf1a, anticorps tif1, anticorps tif1a, anticorps tif1alpha, anticorps A130082H20Rik, anticorps AI447469, anticorps D430004I05Rik, anticorps TIF1-alpha, anticorps TIF1alpha, anticorps Tif1a, anticorps tripartite motif containing 24, anticorps transcription intermediary factor 1-alpha, anticorps tripartite motif containing 24 S homeolog, anticorps tripartite motif-containing 24, anticorps TRIM24, anticorps trim24, anticorps LOC100548578, anticorps trim24.S, anticorps Trim24
    Sujet

    Description: Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes (By similarity).

    Gene: TRIM24

    Poids moléculaire
    117kDa
    ID gène
    8805
    UniProt
    O15164
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