USP14 anticorps (Internal Region)
-
- Antigène Voir toutes USP14 Anticorps
- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
-
Épitope
- Internal Region
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp USP14 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Specificité
- USP14 Antibody detects endogenous levels of total USP14.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human USP14, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product USP14 Anticorps primaire
-
-
- Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
-
- Antigène
- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
- Autre désignation
- USP14 (USP14 Produits)
- Synonymes
- anticorps TGT, anticorps DDBDRAFT_0202821, anticorps DDBDRAFT_0237695, anticorps DDB_0202821, anticorps DDB_0237695, anticorps 2610005K12Rik, anticorps 2610037B11Rik, anticorps AW107924, anticorps C78769, anticorps ax, anticorps zgc:55949, anticorps wu:fk63d09, anticorps MGC81945, anticorps tgt, anticorps MGC69343, anticorps USP14, anticorps ubiquitin specific peptidase 14, anticorps peptidase C19 family protein, anticorps ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase), anticorps ubiquitin specific protease 14, anticorps ubiquitin specific peptidase 14 S homeolog, anticorps universal stress protein, anticorps Ubiquitin carboxyl-terminal hydrolase 14, anticorps USP14, anticorps usp14, anticorps Usp14, anticorps Bm1_28765, anticorps usp14.S, anticorps RR_RS06480, anticorps usp-14
- Sujet
-
Description: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.
Gene: USP14
- Poids moléculaire
- 56 kDa
- ID gène
- 9097
- UniProt
- P54578
-