WNT7A anticorps (Internal Region)

N° du produit ABIN6266046

Détail du produit anti-WNT7A anticorps

Antigène: WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT7A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Wnt7a Antibody detects endogenous levels of total Wnt7a.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Wnt7a, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur WNT7A

Antigène: WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))

Autre désignation: WNT7A (WNT7A Produits)

Synonymes: anticorps wnt7a, anticorps AI849442, anticorps Wnt-7a, anticorps px, anticorps tw, anticorps Xwnt-7a, anticorps wnt-7a, anticorps wnt7a-A, anticorps Wnt family member 7A, anticorps wingless-type MMTV integration site family, member 7Aa, anticorps wingless-type MMTV integration site family, member 7A, anticorps wingless-type MMTV integration site family member 7A S homeolog, anticorps WNT7A, anticorps wnt7aa, anticorps Wnt7a, anticorps wnt7a.S

Sujet:

Description: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development (PubMed:16826533). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal neural stem cell proliferation in the hippocampus dentate gyrus. Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation. Promotes formation of synapses via its interaction with FZD5 (By similarity).

Gene: WNT7A

Poids moléculaire: 39kDa

ID gène: 7476

UniProt: O00755

Pathways: Signalisation WNT, Stem Cell Maintenance, Asymmetric Protein Localization