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SIP1 anticorps (N-Term)

GEMIN2 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6266294
  • Antigène Voir toutes SIP1 (GEMIN2) Anticorps
    SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
    Épitope
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 38
    • 25
    • 24
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 34
    • 5
    Lapin
    Clonalité
    • 35
    • 4
    Polyclonal
    Conjugué
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SIP1 est non-conjugé
    Application
    • 19
    • 14
    • 10
    • 9
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    GEMIN2 Antibody detects endogenous levels of total GEMIN2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human GEMIN2, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GEMIN2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
    Autre désignation
    GEMIN2 (GEMIN2 Produits)
    Synonymes
    anticorps SIP1, anticorps SIP1-delta, anticorps 1700012N19Rik, anticorps Sip1, anticorps sip1, anticorps sip1-delta, anticorps wu:fc52a05, anticorps zgc:110274, anticorps gem nuclear organelle associated protein 2, anticorps gem (nuclear organelle) associated protein 2, anticorps gem nuclear organelle associated protein 2 S homeolog, anticorps GEMIN2, anticorps Gemin2, anticorps gemin2.S, anticorps gemin2
    Sujet

    Description: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

    Gene: GEMIN2

    Poids moléculaire
    32kDa
    ID gène
    8487
    UniProt
    O14893
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Tube Formation
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