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RACGAP1 anticorps (pSer387)

RACGAP1 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6267691
  • Antigène Voir toutes RACGAP1 Anticorps
    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
    Épitope
    • 20
    • 15
    • 13
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer387
    Reactivité
    • 74
    • 32
    • 26
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    Humain, Souris, Rat, Singe
    Hôte
    • 83
    • 4
    • 2
    • 1
    Lapin
    Clonalité
    • 85
    • 5
    Polyclonal
    Conjugué
    • 48
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp RACGAP1 est non-conjugé
    Application
    • 82
    • 41
    • 35
    • 33
    • 26
    • 26
    • 15
    • 15
    • 10
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Phospho-GTPase Activating Protein (Ser387) Antibody detects endogenous levels of GTPase Activating Protein only when phosphorylated at Serine 387
     Réactivité croisée
    Humain, Singe, Souris, Rat (Rattus)
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogène
    A synthesized peptide derived from human GTPase Activating Protein around the phosphorylation site of Serine 387
    Isotype
    IgG
    Top Product
    Discover our top product RACGAP1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
    Autre désignation
    GTPase Activating Protein (RACGAP1 Produits)
    Synonymes
    anticorps CYK4, anticorps HsCYK-4, anticorps ID-GAP, anticorps MgcRacGAP, anticorps cyk-4, anticorps id-gap, anticorps mgcracgap, anticorps RACGAP1, anticorps MGC121578, anticorps Gap, anticorps RasGAP, anticorps Rasa, anticorps GAPX, anticorps AI227039, anticorps AI327394, anticorps Band25, anticorps GTPase, anticorps gtl11, anticorps mKIAA1478, anticorps wu:fb92c08, anticorps zgc:77839, anticorps Rac GTPase activating protein 1, anticorps rac GTPase-activating protein 1, anticorps Rac GTPase activating protein 1 L homeolog, anticorps RAS p21 protein activator 1, anticorps Rac GTPase-activating protein 1, anticorps si:ch1073-416j23.1, anticorps RACGAP1, anticorps racgap1, anticorps racgap1.L, anticorps racgap1.2.L, anticorps racgap1.2, anticorps Rasa1, anticorps Racgap1, anticorps si:ch1073-416j23.1
    Sujet

    Description: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

    Gene: RACGAP1

    Poids moléculaire
    72kDa
    ID gène
    29127
    UniProt
    Q9H0H5
    Pathways
    Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
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