ADRB3 anticorps (Internal Region)

N° du produit ABIN6282314

Détail du produit anti-ADRB3 anticorps

Antigène: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Épitope: AA 220-300, Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRB3 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: AR-β3 is a protein encoded by the ADRB3 gene which is approximately 43,5 kDa. AR-β3 is localised to the cell membrane. It is involved in peptide ligand-binding receptors, activation of cAMP-dependent PKA, signalling by GPCR and DAG and IP3 signalling. It mediates catecholamine-induced activation of adenylate cyclase through the action of G proteins and is involved in the regulation of lipolysis and thermogenesis. AR-β3 is expressed mainly in adipose tissue. Mutations in the ADRB3 gene may be involved in diabetes mellitus and obesity. STJ91728 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of AR-β3 protein.

Specificité: AR-β3 Polyclonal Antibody detects endogenous levels of AR-β3 protein.

Attributs du produit: Rabbit polyclonal to AR-β3.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human AR-beta3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
ELISA 1:20000

Commentaires:

Expressed mainly in adipose tissues.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur ADRB3

Antigène: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Autre désignation: AR-beta3 (ADRB3 Produits)

Synonymes: anticorps BETA3AR, anticorps Adrb-3, anticorps ADRB, anticorps BAR3, anticorps B3AR, anticorps GPCR, anticorps im:7154935, anticorps si:ch211-215f19.1, anticorps zgc:194843, anticorps zgc:194852, anticorps adrenoceptor beta 3, anticorps adrenergic receptor, beta 3, anticorps adrenoceptor beta 3a, anticorps adrenoceptor beta 3b, anticorps ADRB3, anticorps Adrb3, anticorps adrb3a, anticorps adrb3b

Poids moléculaire: 36 kDa

ID gène: 155

UniProt: P13945

Pathways: cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation