PKC anticorps (AA 600-680)

N° du produit ABIN6284619

Détail du produit anti-PKC anticorps

Antigène: PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))

Épitope: AA 600-680

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: PKC is a protein encoded by the PRKCA gene which is approximately 76,7 kDa. PKC is localised to the cytoplasm and cell membrane. It is involved in RET signalling, DAG and IP3 signalling, the IL-2 Pathway, fMLP pathway and CDK-mediated phosphorylation and removal of Cdc6. It is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. It plays a role in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. PKC is expressed in the liver, blood, nervous system, skin and pancreas. Mutations in the PRKCA gene may result in glioma and myotonic dystrophy. STJ95117 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PKC protein.

Specificité: PKC Polyclonal Antibody detects endogenous levels of PKC protein.

Attributs du produit: Rabbit polyclonal to PKC.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human PKC around the non-phosphorylation site of T497.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur PKC

Antigène: PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))

Autre désignation: PKC (PKC pan Produits)

Synonymes: anticorps PKC, anticorps PKCI, anticorps Prkc, anticorps Prkcc, anticorps RATPKCI, anticorps protein kinase C, gamma, anticorps Prkcg

Poids moléculaire: 85 kDa

ID gène: 5578

UniProt: P17252

Pathways: Positive Regulation of Response to DNA Damage Stimulus