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JAG1 anticorps (Internal Region)

JAG1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6285442
  • Antigène Voir toutes JAG1 Anticorps
    JAG1 (Jagged 1 (JAG1))
    Épitope
    • 12
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 981-1030, Internal Region
    Reactivité
    • 78
    • 36
    • 29
    • 1
    Humain, Souris, Rat
    Hôte
    • 67
    • 15
    • 3
    • 2
    • 1
    Lapin
    Clonalité
    • 64
    • 24
    Polyclonal
    Conjugué
    • 40
    • 9
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp JAG1 est non-conjugé
    Application
    • 62
    • 31
    • 26
    • 18
    • 11
    • 11
    • 9
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Jagged1 is a protein encoded by the JAG1 gene which is approximately 133,7 kDa. Jagged1 is localised to the plasma membrane. It is involved in signalling by Notch1, Notch2 activation and transmission of signal to the nucleus and the HIV life cycle. It is a ligand for multiple Notch receptors and may also be involved in cell-fate decisions during hematopoiesis and in the early and late stages of mammalian cardiovascular development. Jagged1 is widely expressed in adult and foetal tissues. Mutations in the JAG1 gene may result in Alagille syndrome. STJ96766 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Jagged1 protein.
    Specificité
    Jagged1 Polyclonal Antibody detects endogenous levels of Jagged1 protein.
    Attributs du produit
    Rabbit polyclonal to Jagged1.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    Synthesized peptide derived from human Jagged1.
    Isotype
    IgG
    Top Product
    Discover our top product JAG1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    IHC-P 1:100-1:300
    ELISA 1:20000
    Commentaires

    Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Antigène
    JAG1 (Jagged 1 (JAG1))
    Autre désignation
    Jagged1 (JAG1 Produits)
    Synonymes
    anticorps AGS, anticorps AHD, anticorps AWS, anticorps CD339, anticorps HJ1, anticorps JAGL1, anticorps ABE2, anticorps Gsfabe2, anticorps Htu, anticorps Ozz, anticorps Ser-1, anticorps JAG1, anticorps jag3, anticorps cb243, anticorps jag1, anticorps sb:cb243, anticorps serrateC, anticorps jagged1, anticorps serrate, anticorps serrate-1, anticorps x-serrate-1, anticorps jagged 1, anticorps jagged 1b, anticorps jagged 1a, anticorps jagged 1 L homeolog, anticorps JAG1, anticorps Jag1, anticorps jag1, anticorps jag1b, anticorps jag1a, anticorps jag1.L
    Poids moléculaire
    140 kDa
    ID gène
    182
    UniProt
    P78504
    Pathways
    Signalisation Notch, Stem Cell Maintenance
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