TLN1 anticorps (C-Term)
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- Antigène Voir toutes TLN1 Anticorps
- TLN1 (Talin 1 (TLN1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TLN1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Fonction
- Talin-1 is a protein encoded by the TLN1 gene which is approximately 269,2 kDa. Talin-1 is localised to the cytoplasm and cell surface. It is involved in RET signalling, integrin alphaIIb beta3 signalling, response to elevated platelet cytosolic Ca2+ and focal adhesion. It plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It co-distributes with integrins in the cell surface membrane in order to assist in the attachment of lymphocytes to other cells and attachment of adherent cells to extracellular matrices. Talin-1 is expressed in the blood, nervous system, liver, intestine and skin. Mutations in the TLN1 gene result in ovarian serous carcinoma. STJ97271 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Talin-1 protein.
- Specificité
- Talin-1 Polyclonal Antibody detects endogenous levels of Talin-1 protein.
- Attributs du produit
- Rabbit polyclonal to Talin-1.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from human Talin-1.
- Isotype
- IgG
- Top Product
- Discover our top product TLN1 Anticorps primaire
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- Indications d'application
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WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:10000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Antigène
- TLN1 (Talin 1 (TLN1))
- Autre désignation
- Talin-1 (TLN1 Produits)
- Synonymes
- anticorps ILWEQ, anticorps TLN, anticorps Tln, anticorps sb:cb854, anticorps wu:fb05c02, anticorps TLN1, anticorps talin-1, anticorps tln, anticorps talin 1, anticorps talin 1 L homeolog, anticorps Talin 1, anticorps talin-1, anticorps TLN1, anticorps Tln1, anticorps tln1, anticorps tln1.L, anticorps Bm1_56490, anticorps LOC100380665
- ID gène
- 7094
- UniProt
- Q9Y490
- Pathways
- Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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