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TLN1 anticorps (C-Term)

TLN1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6285636
  • Antigène Voir toutes TLN1 Anticorps
    TLN1 (Talin 1 (TLN1))
    Épitope
    • 15
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 42
    • 37
    • 26
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 43
    • 15
    • 1
    • 1
    Lapin
    Clonalité
    • 45
    • 15
    Polyclonal
    Conjugué
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TLN1 est non-conjugé
    Application
    • 30
    • 22
    • 13
    • 13
    • 8
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Fonction
    Talin-1 is a protein encoded by the TLN1 gene which is approximately 269,2 kDa. Talin-1 is localised to the cytoplasm and cell surface. It is involved in RET signalling, integrin alphaIIb beta3 signalling, response to elevated platelet cytosolic Ca2+ and focal adhesion. It plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It co-distributes with integrins in the cell surface membrane in order to assist in the attachment of lymphocytes to other cells and attachment of adherent cells to extracellular matrices. Talin-1 is expressed in the blood, nervous system, liver, intestine and skin. Mutations in the TLN1 gene result in ovarian serous carcinoma. STJ97271 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Talin-1 protein.
    Specificité
    Talin-1 Polyclonal Antibody detects endogenous levels of Talin-1 protein.
    Attributs du produit
    Rabbit polyclonal to Talin-1.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    Synthesized peptide derived from human Talin-1.
    Isotype
    IgG
    Top Product
    Discover our top product TLN1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    IHC-P 1:100-1:300
    ELISA 1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Antigène
    TLN1 (Talin 1 (TLN1))
    Autre désignation
    Talin-1 (TLN1 Produits)
    Synonymes
    anticorps ILWEQ, anticorps TLN, anticorps Tln, anticorps sb:cb854, anticorps wu:fb05c02, anticorps TLN1, anticorps talin-1, anticorps tln, anticorps talin 1, anticorps talin 1 L homeolog, anticorps Talin 1, anticorps talin-1, anticorps TLN1, anticorps Tln1, anticorps tln1, anticorps tln1.L, anticorps Bm1_56490, anticorps LOC100380665
    ID gène
    7094
    UniProt
    Q9Y490
    Pathways
    Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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